Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 6/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8373355 | 0.85 | GPR35 (0.57) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL7766735 | 0.83 | GPR35 (0.49) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL31447707 | 0.79 | ALDH1A1 (0.53) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL29837196 | 0.79 | ALDH1A1 (0.53) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL4649869 | 0.79 | ALDH1A1 (0.53) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL9316398 | 0.76 | GPR35 (0.66) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL10671642 | 0.74 | ALDH1A1 (0.58) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL29836953 | 0.74 | ALDH1A1 (0.55) | TTRALDH1A1HPGDALOX15HIF1A | |
| SCHEMBL3858194 | 0.72 | TTR (0.67) | TTRGPR35ALDH1A1HPGDALOX15 | |
| SCHEMBL18306136 | 0.71 | TTR (0.67) | TTRGPR35ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977413-A | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0895985-A2 | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | Nippon Kayaku Kabushiki Kaisha (JP) | 1999-02-10 | — | — | EP | disclosed |