SCHEMBL837424

SCHEMBL837424

CCCC/C=C/[Si](OCC)(OCC)OCC

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 3/20 0.33
TSHR P16473 3/20 0.33
ALDH1A1 P00352 2/20 0.33
LPAR2 Q9HBW0 2/20 0.32
LPAR1 Q92633 1/20 0.32
F7 P08709 1/20 0.32
F3 P13726 1/20 0.32
FAAH O00519 4/20 0.32
TRPV1 Q8NER1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL837425 1.00 LPAR3 (0.33) LPAR3TSHRALDH1A1LPAR2LPAR1
SCHEMBL14976611 0.93 FAAH (0.40) LPAR3TSHRALDH1A1FAAHTRPV1
SCHEMBL14976610 0.93 FAAH (0.40) LPAR3TSHRALDH1A1FAAHTRPV1
SCHEMBL930992 0.92 LPAR3 (0.33) LPAR3LPAR2LPAR1
SCHEMBL930549 0.92 LPAR3 (0.33) LPAR3LPAR2LPAR1
SCHEMBL2802636 0.91 FAAH (0.43) LPAR3F7F3FAAHTRPV1
SCHEMBL388914 0.91 FAAH (0.43) LPAR3F7F3FAAHTRPV1
SCHEMBL19125743 0.91 FAAH (0.43) LPAR3F7F3FAAHTRPV1
SCHEMBL16459844 0.91 FAAH (0.43) LPAR3F7F3FAAHTRPV1
SCHEMBL3483604 0.91 FAAH (0.43) LPAR3F7F3FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 446 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240043608-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2024-02-08 US claimed
US-10633484-B2 Method and composition for improving adhesion of metathesis compositions to substrates MATERIA, INC. (US) 2020-04-28 US claimed
EP-2782951-B1 LOW CHLORIDE COMPOSITIONS OF OLEFINICALLY FUNCTIONALISED SILOXANE OLIGOMERS BASED ON ALKOXYSILANES EVONIK DEGUSSA GMBH (DE) 2019-01-02 EP claimed
US-10059857-B2 Method and composition for improving adhesion of metathesis compositions to substrates MATERIA, INC. (US) 2018-08-28 US claimed
US-20180237581-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2018-08-23 US claimed
EP-2782953-B1 COMPOSITION OF OLEFINICALLY FUNCTIONALSIED SILOXANE OLIGOMERS BASED ON ALKOXY SILANES EVONIK DEGUSSA GMBH (DE) 2018-07-25 EP claimed
US-9828392-B2 Low chloride compositions of olefinically functionalised siloxane oligomers based on alkoxysilanes EVONIK DEGUSSA GMBH (DE) 2017-11-28 US claimed
US-20170130089-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES MATERIA, INC. (US) 2017-05-11 US claimed
EP-3092204-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES Materia, Inc. (US) 2016-11-16 EP claimed
US-20160326304-A1 METHOD AND COMPOSITION FOR IMPROVING ADHESION OF METATHESIS COMPOSITIONS TO SUBSTRATES ExxonMobil Product Solutions Company 2016-11-10 US claimed
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2011-03-31 US claimed
EP-2276793-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS Essilor International (Compagnie Générale d'Optique) (FR) 2011-01-26 EP claimed
WO-2009138853-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS ESSILOR INTERNATIONAL (FR) 2009-11-19 WO claimed
EP-1235877-B1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING (US) 2005-03-23 EP claimed
EP-1235877-A1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING CORPORATION (US) 2002-09-04 EP claimed
WO-2001019914-A1 THERMOPLASTIC SILICONE ELASTOMERS BASED ON FLUOROCARBON RESIN DOW CORNING CORPORATION (US) 2001-03-22 WO claimed
EP-0781823-B1 Primer composition and adhesion method DOW CORNING TORAY SILICONE (JP) 2000-07-12 EP claimed
US-6015858-A CURING; TENSILE STRENGTH, ELONGATION DOW CORNING CORPORATION (US) 2000-01-18 US claimed
US-5973067-A ORGANOSILICON COMPOUND SELECTED FROM THE GROUP CONSISTING OF ALKENYLTRIALKOXYSILANE OR HYDROLYZATES THEREOF, A PLATINUM COMPOUND, AN ORGANIC TITANIC ACID; FOR PROMOTING THE ADHESION OF THERMOSETTING RUBBERS TO SUBSTRATES DOW CORNING TORAY SILICONE CO., LTD. (JP) 1999-10-26 US claimed
EP-0781823-A1 Primer composition and adhesion method Dow Corning Toray Silicone Company, Limited (JP) 1997-07-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110077341-A1 SULFUR MODIFIED SILANES FOR THE ELABORATION OF HIGH REFRACTIVE INDEX MATERIALS TST, LAGE3, PSME1 LPAR3 1934/4885TSHR 3396/4885ALDH1A1 814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.