SCHEMBL8375012

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19682791	0.86	HPRT1 (0.42)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL4569234	0.84	NCEH1 (0.45)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL18243139	0.78	ALDH1A1 (0.42)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL18242403	0.78	CYP1A2 (0.52)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL8377379	0.77	CYP2A6 (0.50)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL15750882	0.77	KMT2A (0.53)	ALDH1A1HSD17B10TDP1CYP1A2MAPT
	SCHEMBL18244135	0.77	ALDH1A1 (0.41)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL3674343	0.76	ALDH1A1 (0.44)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL18242235	0.76	ATM (0.41)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL15750673	0.74	MAPT (0.56)	ALDH1A1HSD17B10NCEH1CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.