SCHEMBL19682791

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8375012	0.86	HPRT1 (0.41)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL4569234	0.86	NCEH1 (0.45)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL19682355	0.78	CYP1A2 (0.54)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL3674343	0.78	ALDH1A1 (0.44)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL29853842	0.74	ALDH1A1 (0.42)	ALDH1A1CYP2A6TSHRHSD17B10TDP1
	SCHEMBL4642610	0.74	ALDH1A1 (0.42)	ALDH1A1CYP2A6TSHRHSD17B10TDP1
	SCHEMBL4828643	0.73	CES2 (0.39)	TDP1
	SCHEMBL20889374	0.72	AKR1C3 (0.42)	ALDH1A1NCEH1MAPTMAPK1L3MBTL1
	SCHEMBL6858138	0.72	CYP1A2 (0.45)	HPRT1ALDH1A1CYP2A6TSHRHSD17B10
	SCHEMBL22331223	0.70	—	—

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.