Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Amiloxate SCHEMBL29696497 | 0.94 | LMNA (0.76) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL6162547 | 0.86 | TDP1 (0.57) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL196087 | 0.84 | LMNA (0.50) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL30485146 | 0.82 | LMNA (0.57) | TDP1LMNAAPPMEN1KMT2A | |
| SCHEMBL39355 | 0.82 | LMNA (0.72) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL39354 | 0.82 | LMNA (0.72) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| Cinoxate SCHEMBL30139914 | 0.81 | LMNA (0.53) | TDP1LMNASMN1; SMN2APPMEN1 | |
| Amiloxate SCHEMBL2228053 | 0.81 | LMNA (1.00) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| Amiloxate SCHEMBL15765 | 0.81 | LMNA (1.00) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 | |
| Amiloxate SCHEMBL15764 | 0.81 | LMNA (1.00) | TDP1LMNASMN1; SMN2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0901512-A1 | DETERGENT COMPOSITION | UNILEVER PLC (GB) | 1999-03-17 | — | — | EP | disclosed |
| WO-1997044422-A1 | DETERGENT COMPOSITION | UNILEVER PLC (GB) | 1997-11-27 | — | — | WO | disclosed |