Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156710 | 0.85 | TGFBR1 (0.61) | TGFBR1LMNACA2CA1RNPEP | |
| SCHEMBL6156715 | 0.85 | TGFBR1 (0.61) | TGFBR1LMNACA2CA1RNPEP | |
| SCHEMBL1694616 | 0.82 | CA12 (0.44) | CA12CA9TSHRLMNACA2 | |
| SCHEMBL1694618 | 0.82 | CA12 (0.44) | CA12CA9TSHRLMNACA2 | |
| SCHEMBL11032203 | 0.82 | CA12 (0.44) | CA12CA9TSHRLMNACA2 | |
| SCHEMBL538340 | 0.80 | TSHR (0.54) | CA12CA9TSHRLMNACA2 | |
| SCHEMBL538339 | 0.80 | TSHR (0.54) | CA12CA9TSHRLMNACA2 | |
| SCHEMBL21585750 | 0.79 | TGFBR1 (0.49) | TGFBR1CA12CA9CA2CA1 | |
| SCHEMBL2969793 | 0.79 | TGFBR1 (0.49) | TGFBR1CA12CA9CA2CA1 | |
| SCHEMBL8374365 | 0.77 | TGFBR1 (0.69) | TGFBR1CA12CA9CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883211-A | Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis | ACLARA BIOSCIENCES, INC. (US) | 1999-03-16 | — | — | US | disclosed |
| WO-1997040078-A1 | THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS | SOANE BIOSCIENCES (US) | 1997-10-30 | — | — | WO | disclosed |