SCHEMBL8375446

SCHEMBL8375446

C=C(C)CNC(CCC(N)=O)C(N)=O

nearest known ligand 0.34

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.34
ALOX15 P16050 1/20 0.34
BLM P54132 1/20 0.34
PMP22 Q01453 1/20 0.34
DPP4 P27487 1/20 0.33
DPP8 Q6V1X1 1/20 0.33
DPP9 Q86TI2 1/20 0.33
BMP1 P13497 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31
MMP2 P08253 2/20 0.31
MMP9 P14780 2/20 0.31
CA2 P00918 2/20 0.30
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374062 0.81 ECE1 (0.38)
SCHEMBL23350131 0.80 ALDH1A1 (0.31)
SCHEMBL26267822 0.80 ALDH1A1 (0.31)
SCHEMBL8374364 0.79 TGFBR1 (0.40)
SCHEMBL8375418 0.79 TSHR (0.36) KMT2ACA2CA1
SCHEMBL8376823 0.79 SIRT6 (0.38) CA2CA1
SCHEMBL8378525 0.78 KDM4E (0.38) ALOX15BLMCA1
SCHEMBL24735318 0.78 BMP1 (0.32) BMP1
SCHEMBL8373319 0.76 ALDH1A1 (0.40) KMT2AMMP2MMP9CA1
SCHEMBL2969793 0.75 TGFBR1 (0.49) KMT2AALOX15BLMPMP22DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5883211-A Thermoreversible hydrogels comprising linear copolymers and their use in electrophoresis ACLARA BIOSCIENCES, INC. (US) 1999-03-16 US disclosed
WO-1997040078-A1 THERMOREVERSIBLE HYDROGELS COMPRISING NON-CROSSLINKED COPOLYMERS AND THEIR USE IN ELECTROPHORESIS SOANE BIOSCIENCES (US) 1997-10-30 WO disclosed