Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.35 |
| ▸ | RAB9A | P51151 | 8/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378889 | 0.90 | CXCR1 (0.32) | CYP1A2CYP19A1CYP2C9CYP2C19CXCR1 | |
| SCHEMBL8379540 | 0.90 | ALDH1A1 (0.38) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL8376906 | 0.90 | CXCR1 (0.40) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL8375770 | 0.90 | CXCR1 (0.43) | NPC1RAB9ASMN1; SMN2HPGDCXCR1 | |
| SCHEMBL8375559 | 0.90 | CXCR1 (0.41) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL8378946 | 0.90 | CXCR1 (0.40) | ALDH1A1CXCR1 | |
| SCHEMBL8375816 | 0.89 | EPHX2 (0.38) | CYP1A2CYP19A1CYP2C9CYP2C19CXCR1 | |
| SCHEMBL8380142 | 0.89 | HPGD (0.42) | NPC1RAB9ACYP1A2CYP19A1CYP2C9 | |
| SCHEMBL8374994 | 0.88 | THRB (0.38) | CYP1A2CYP19A1CYP2C9CYP2C19LMNA | |
| SCHEMBL8378839 | 0.86 | CXCR1 (0.45) | NPC1RAB9ALMNAALDH1A1CXCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6005116-A | HAVE INHIBITION ACTIVITIES AGAINST TYPE A-MONOAMINE OXIDASE; TREATING OR PREVENTING DEPRESSION, PARKINSON'S DISEASE, ALZEHEIMER'S DEMENTIA, OR CEREBROVASCULAR DEMENTIA | SANKYO COMPANY, LIMITED (JP) | 1999-12-21 | — | — | US | disclosed |
| EP-0885891-A1 | ISOXAZOLE DERIVATIVES | SANKYO COMPANY LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |