Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10793703 | 0.78 | ALDH1A1 (0.37) | ALDH1A1TSHRMAPTRAB9A | |
| SCHEMBL10798486 | 0.76 | PSEN1 (0.37) | ALDH1A1CYP3A4ALOX15HSD17B10MAPT | |
| SCHEMBL7937151 | 0.74 | TDP1 (0.59) | SMN1; SMN2ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL10792590 | 0.73 | MAPT (0.38) | SMN1; SMN2ALDH1A1ALOX15L3MBTL1MAPT | |
| SCHEMBL10796787 | 0.73 | KMT2A (0.40) | SMN1; SMN2ALDH1A1TP53L3MBTL1MAPT | |
| SCHEMBL7720749 | 0.73 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1TP53HSP90AA1CYP3A4 | |
| SCHEMBL10792949 | 0.72 | KMT2A (0.44) | SMN1; SMN2ALDH1A1TP53TSHRMAPT | |
| SCHEMBL10793005 | 0.72 | KIF11 (0.37) | SMN1; SMN2ALDH1A1TP53CYP3A4ALOX15 | |
| SCHEMBL10792618 | 0.71 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1CYP3A4TSHRHSD17B10 | |
| SCHEMBL10792612 | 0.71 | ESR1 (0.38) | SMN1; SMN2ALDH1A1HSP90AA1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11140001-A | — | — | None | — | — | JP | disclosed |
| JP-H11140001-A | PREVENTION OF POLYMERIZATION OF AROMATIC VINYL COMPOUND DURING DISTILLATION | UOP LLC | 1999-05-25 | — | — | JP | disclosed |
| EP-0903331-A1 | Process for inhibiting polymerization during distillation of vinyl aromatics | UOP (US) | 1999-03-24 | — | — | EP | disclosed |