Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 8/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10792605 | 0.84 | CHRNB2 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10793703 | 0.83 | ALDH1A1 (0.37) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10792949 | 0.77 | KMT2A (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10794057 | 0.77 | PSEN1 (0.41) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL10793005 | 0.77 | KIF11 (0.37) | HTTCYP3A4KDM4EALDH1A1ALOX15 | |
| SCHEMBL10792618 | 0.76 | ALDH1A1 (0.50) | CYP3A4ALDH1A1HSD17B10MAPTRORC | |
| SCHEMBL10792612 | 0.76 | ESR1 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL8375618 | 0.76 | SMN1; SMN2 (0.36) | CYP3A4ALDH1A1ALOX15HSD17B10MAPT | |
| SCHEMBL7102244 | 0.75 | — | — | |
| SCHEMBL4295727 | 0.72 | ALDH1A1 (0.31) | KDM4EALDH1A1HPGDALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4675445-A | Process for elimination N-nitrosamines from N-nitrosamine-containing compositions | BASF CORPORATION (US) | 1987-06-23 | — | — | US | disclosed |