Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 2/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | TTR | P02766 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310541 | 0.87 | SNCA (0.46) | SNCAGPR35MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL15797126 | 0.84 | XDH (0.44) | SNCAGPR35MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL518140 | 0.82 | GPR35 (0.50) | SNCAGPR35MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL2326899 | 0.80 | TDP1 (0.50) | SNCAGPR35MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL30031583 | 0.80 | TDP1 (0.50) | SNCAGPR35MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL7976613 | 0.78 | PDGFRB (0.51) | SNCAMAPK1ALDH1A1TTRALOX15 | |
| SCHEMBL8067566 | 0.76 | MAPK1 (0.52) | GPR35MAPK1ALDH1A1HSD17B10TTR | |
| SCHEMBL744876 | 0.76 | TDP1 (0.46) | SNCAGPR35MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL309964 | 0.76 | GPR35 (0.48) | GPR35MAPK1ALDH1A1HSD17B10TTR | |
| SCHEMBL309310 | 0.76 | ALDH1A1 (0.49) | GPR35MAPK1ALDH1A1HSD17B10TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977413-A | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0895985-A2 | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | Nippon Kayaku Kabushiki Kaisha (JP) | 1999-02-10 | — | — | EP | disclosed |