SCHEMBL309310

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6482217	0.92	ALDH1A1 (0.49)	ALDH1A1CYP3A4GPR35MAPK1TTR
	SCHEMBL2797010	0.85	ALDH1A1 (0.49)	ALDH1A1CYP3A4GPR35MAPK1TTR
	SCHEMBL518140	0.84	GPR35 (0.50)	ALDH1A1GPR35MAPK1TTRHPGD
	SCHEMBL305109	0.84	ALDH1A1 (0.55)	ALDH1A1CYP3A4GPR35MAPK1TTR
	SCHEMBL138641	0.82	TDP1 (0.50)	ALDH1A1CYP3A4GPR35MAPK1HPGD
	SCHEMBL30953155	0.82	TDP1 (0.50)	ALDH1A1CYP3A4GPR35MAPK1HPGD
	SCHEMBL9694173	0.82	TSHR (0.50)	ALDH1A1CYP3A4GPR35MAPK1HPGD
	SCHEMBL11555308	0.82	ALDH1A1 (0.69)	ALDH1A1CYP3A4GPR35MAPK1TTR
	SCHEMBL30031583	0.82	TDP1 (0.50)	ALDH1A1GPR35MAPK1TTRHPGD
	SCHEMBL2326899	0.82	TDP1 (0.50)	ALDH1A1GPR35MAPK1TTRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.