Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.40 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3153767 | 0.94 | MAPT (0.40) | MBTD1L3MBTL3L3MBTL1MAPTNPSR1 | |
| Methane SCHEMBL27848146 | 0.92 | MAPT (0.39) | MBTD1L3MBTL3L3MBTL1MAPTNPSR1 | |
| SCHEMBL11611267 | 0.85 | L3MBTL1 (0.36) | MBTD1L3MBTL3L3MBTL1MAPTNPSR1 | |
| SCHEMBL5352313 | 0.85 | MAPT (0.42) | MBTD1L3MBTL3L3MBTL1MAPTNPSR1 | |
| SCHEMBL1968507 | 0.78 | L3MBTL1 (0.38) | MBTD1L3MBTL3L3MBTL1MAPTNPSR1 | |
| SCHEMBL29507810 | 0.75 | CHKA (0.48) | L3MBTL1MAPTNPSR1ALDH1A1TDP1 | |
| SCHEMBL28217503 | 0.73 | ALDH1A1 (0.39) | MAPTNPSR1MAPK1HTTNPC1 | |
| SCHEMBL28380433 | 0.72 | LMNA (0.31) | L3MBTL1MAPTNPSR1TDP1LMNA | |
| SCHEMBL4164157 | 0.71 | SIGMAR1 (0.38) | MBTD1L3MBTL3L3MBTL1MAPTNPSR1 | |
| SCHEMBL12474038 | 0.71 | CYP2D6 (0.34) | HTTCYP3A4CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934068-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0901787-A1 | Stabilized pharmaceutical composition | Takeda Chemical Industries, Ltd. (JP) | 1999-03-17 | — | — | EP | disclosed |
| WO-1998009630-A1 | COMPOUNDS AND METHODS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-03-12 | — | — | WO | disclosed |