Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.45 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.45 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8376166 | 0.94 | P4HB (0.45) | P4HBPDIA4PDIA3SLC5A1CA12 | |
| SCHEMBL8380405 | 0.80 | SLC5A1 (0.70) | SLC5A1CYP3A4CYP2C9 | |
| SCHEMBL1726710 | 0.77 | P4HB (0.61) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL8654501 | 0.77 | P4HB (0.61) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL8378697 | 0.75 | MEN1 (0.41) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL12651482 | 0.75 | P4HB (0.63) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL12651491 | 0.75 | P4HB (0.63) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL20633976 | 0.74 | P4HB (0.61) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL8376188 | 0.74 | P4HB (0.57) | P4HBPDIA4PDIA3CA12CA1 | |
| SCHEMBL8376183 | 0.74 | P4HB (0.57) | P4HBPDIA4PDIA3CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684254-B1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5830873-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0684254-A1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |