Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.40 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377320 | 0.87 | MEN1 (0.39) | MEN1CYP3A4KMT2ALMNAUSP2 | |
| SCHEMBL8376166 | 0.77 | P4HB (0.45) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL8376084 | 0.75 | P4HB (0.45) | MEN1CYP3A4KMT2ATP53CYP2C9 | |
| SCHEMBL13063347 | 0.73 | MEN1 (0.56) | MEN1CYP3A4KMT2ALMNAUSP2 | |
| SCHEMBL8377328 | 0.71 | SLC5A1 (0.59) | CYP3A4KDM4EMAPTHSD17B10CYP2C9 | |
| SCHEMBL10964418 | 0.70 | MEN1 (0.52) | MEN1CYP3A4KMT2ALMNAUSP2 | |
| SCHEMBL18272754 | 0.70 | HSD17B10 (0.51) | MEN1CYP3A4KMT2ALMNAUSP2 | |
| SCHEMBL1726710 | 0.69 | P4HB (0.61) | HSD17B10P4HBPDIA4PDIA3TSHR | |
| SCHEMBL8654501 | 0.69 | P4HB (0.61) | HSD17B10P4HBPDIA4PDIA3TSHR | |
| SCHEMBL12651491 | 0.69 | P4HB (0.63) | HSD17B10P4HBPDIA4PDIA3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0684254-B1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5830873-A | ANTIDIABETIC AGENT | TANABE SEIYAKU CO., LTD. (JP) | 1998-11-03 | — | — | US | disclosed |
| EP-0684254-A1 | Propiophenone derivative and a process for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |