Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3628428 | 0.78 | LMNA (0.42) | — | |
| SCHEMBL2088586 | 0.78 | DNM1 (0.35) | — | |
| SCHEMBL8372327 | 0.77 | TSHR (0.31) | — | |
| SCHEMBL17937692 | 0.76 | — | — | |
| SCHEMBL8412794 | 0.76 | OPRM1 (0.42) | — | |
| SCHEMBL477575 | 0.76 | ENPEP (0.32) | — | |
| SCHEMBL357385 | 0.76 | — | — | |
| SCHEMBL3790732 | 0.74 | OPRM1 (0.41) | — | |
| SCHEMBL4733101 | 0.74 | OPRM1 (0.41) | — | |
| SCHEMBL6303888 | 0.74 | OPRM1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2785726-B1 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | claimed |
| US-5446181-A | Method and apparatus for preparing 3-[N-(2-aminoethyl)]aminopropylalkoxysilane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | claimed |
| EP-3310792-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORP (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-3310793-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORP (US) | 2021-06-09 | — | — | EP | disclosed |
| CN-107743493-B | Process for preparing acryloxysilanes | 美国陶氏有机硅公司 | 2020-10-30 | — | — | CN | disclosed |
| CN-107743492-B | Process for preparing acryloxysilanes | 美国陶氏有机硅公司 | 2020-07-17 | — | — | CN | disclosed |
| US-10273254-B2 | Process for preparing an acryloyloxysilane | DOW CORNING CORPORATION (US) | 2019-04-30 | — | — | US | disclosed |
| US-10246473-B2 | Process for preparing an acryloyloxysilane | DOW CORNING CORPORATION (US) | 2019-04-02 | — | — | US | disclosed |
| EP-2785726-B1 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | disclosed |
| US-20180155371-A1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-20180134734-A1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORPORATION | 2018-05-17 | — | — | US | disclosed |
| WO-2013081820-A2 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF;AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW CORNING CORPORATION (US) | 2013-06-06 | — | — | WO | disclosed |
| EP-2573092-A1 | Method for the preparation and use of bis (alkoxysilylorgano)-dicarboxylates | Dow Corning Corporation (US) | 2013-03-27 | — | — | EP | disclosed |
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | DOW CORNING CORPORATION (US) | 2013-03-21 | — | — | US | disclosed |
| WO-2012050761-A2 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW CORNING CORPORATION (US) | 2012-04-19 | — | — | WO | disclosed |
| EP-0595488-B1 | Method and apparatus for preparing 3-[N-(2-aminoethyl)]aminopropylalkoxysilane | SHINETSU CHEMICAL CO (JP) | 1999-03-03 | — | — | EP | disclosed |
| US-5446181-A | Method and apparatus for preparing 3-[N-(2-aminoethyl)]aminopropylalkoxysilane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| US-5371216-A | Pyridinium salts containing alkoxysilyl groups | HULS AKTIENGESELLSCHAFT (DE) | 1994-12-06 | — | — | US | disclosed |
| EP-0595488-A1 | Method and apparatus for preparing 3-[N-(2-aminoethyl)]aminopropylalkoxysilane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5235051-A | PYRIDINIUM SALTS CONTAINING ALKOXYSILYL GROUPS | HULS AKTIENGESELLSCHAFT (DE) | 1993-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072625-A1 | Method for the Preparation and Use of Bis (Alkoxysilylorgano)-Dicarboxylates | PBRM1, IPMK, BOLA2; BOLA2B | MAPK1 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.