Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378008 | 0.82 | TP53 (0.48) | MAPTGAALMNAHPGDMEN1 | |
| SCHEMBL9486336 | 0.81 | HTR1A (0.39) | MAPTHPGDALDH1A1RHEBTDP1 | |
| SCHEMBL8374153 | 0.79 | MAPT (0.54) | NR1H2MAPTGAALMNAHPGD | |
| SCHEMBL11192792 | 0.79 | NR1H2 (0.52) | NR1H2RAPGEF4MAPTGAALMNA | |
| SCHEMBL9487337 | 0.78 | TUBB4A (0.38) | RAPGEF4MAPTGAALMNAHPGD | |
| SCHEMBL9488033 | 0.77 | MAPT (0.41) | RAPGEF4MAPTGAALMNAHPGD | |
| SCHEMBL11092955 | 0.75 | NR1H2 (0.52) | NR1H2MAPTLMNAHPGDMEN1 | |
| SCHEMBL9486508 | 0.74 | HTR1A (0.43) | RAPGEF4MAPTGAALMNAHPGD | |
| SCHEMBL4801171 | 0.74 | NR1H2 (0.64) | NR1H2RAPGEF4MAPTGAALMNA | |
| SCHEMBL4550104 | 0.71 | MAPT (0.41) | MAPTGAALMNAHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0659801-B1 | Polyimide | MITSUI CHEMICALS INC (JP) | 1999-03-10 | — | — | EP | disclosed |
| US-5484880-A | HEAT RESISTANT POLYMERS FOR APPLIANCES AND INJECTION MOLDED ARTICLES OR FILMS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-16 | — | — | US | disclosed |
| EP-0659801-A1 | Polyimide | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1995-06-28 | — | — | EP | disclosed |