Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | RHEB | Q15382 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9486508 | 0.85 | HTR1A (0.43) | HTR1AHTR3AL3MBTL1ALDH1A1KDM4E | |
| SCHEMBL7059068 | 0.82 | RHEB (0.39) | HTR1AHTR3AL3MBTL1TDP1RHEB | |
| SCHEMBL9487337 | 0.81 | TUBB4A (0.38) | HTR1AHTR3ATUBB4ATUBBTUBA3C | |
| SCHEMBL8377232 | 0.81 | NR1H2 (0.46) | TDP1RHEBALDH1A1MAPTHPGD | |
| SCHEMBL9488033 | 0.80 | MAPT (0.41) | HTR1AHTR3ATDP1CYP1A2CYP2A6 | |
| SCHEMBL9487731 | 0.80 | AR (0.42) | HTR1AHTR3ACYP1A2CYP2A6MAPT | |
| SCHEMBL15509442 | 0.78 | L3MBTL1 (0.45) | HTR1AHTR3AL3MBTL1TDP1SIRT1 | |
| SCHEMBL7674839 | 0.78 | HTR1A (0.50) | HTR1AHTR3AL3MBTL1TDP1CYP1A2 | |
| SCHEMBL15509443 | 0.78 | HPGD (0.42) | HTR1AHTR3AL3MBTL1TDP1SIRT1 | |
| SCHEMBL9486714 | 0.78 | ALDH1A1 (0.49) | HTR1AHTR3AL3MBTL1TDP1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5250657-A | Process for preparing polyarylene thioether | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1993-10-05 | — | — | US | disclosed |
| EP-0440106-A2 | Process for preparing polyarylene thioethers | SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) | 1991-08-07 | — | — | EP | disclosed |