SCHEMBL9487337

SCHEMBL9487337

Cc1cc(C)cc(Sc2cc(C)cc(C)c2C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.38
TUBB P07437 1/20 0.38
TUBA3C P0DPH7 1/20 0.38
IDO1 P14902 1/20 0.38
TUBA1B P68363 1/20 0.38
TUBA4A P68366 1/20 0.38
TUBB4B P68371 1/20 0.38
TUBB3 Q13509 1/20 0.38
TUBB2A Q13885 1/20 0.38
TUBB8 Q3ZCM7 1/20 0.38
TUBA3E Q6PEY2 1/20 0.38
TUBA1A Q71U36 1/20 0.38
TUBA1C Q9BQE3 1/20 0.38
TUBB6 Q9BUF5 1/20 0.38
TUBB2B Q9BVA1 1/20 0.38
TUBB1 Q9H4B7 1/20 0.38
RAPGEF4 Q8WZA2 2/20 0.32
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9488033 0.85 MAPT (0.41) RAPGEF4MEN1LMNATP53GAA
SCHEMBL9486508 0.82 HTR1A (0.43) IDO1RAPGEF4MEN1LMNATP53
SCHEMBL9486336 0.81 HTR1A (0.39) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL8377232 0.78 NR1H2 (0.46) RAPGEF4MEN1LMNATP53GAA
SCHEMBL9488176 0.77 RAPGEF4 (0.32) RAPGEF4MEN1LMNATP53GAA
SCHEMBL9486310 0.77 HTR1A (0.44) TUBB4ATUBBTUBA3CIDO1TUBA1B
SCHEMBL9486972 0.76 MAPT (0.46) TUBB4ATUBBTUBA3CIDO1TUBA1B
SCHEMBL22618598 0.75 RAPGEF4 (0.38) RAPGEF4MEN1LMNATP53GAA
SCHEMBL9191936 0.75 RAPGEF4 (0.38) RAPGEF4MEN1LMNATP53GAA
SCHEMBL8378008 0.75 TP53 (0.48) MEN1LMNATP53GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5250657-A Process for preparing polyarylene thioether SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1993-10-05 US disclosed
EP-0440106-A2 Process for preparing polyarylene thioethers SEISAN KAIHATSU KAGAKU KENKYUSHO (JP) 1991-08-07 EP disclosed