SCHEMBL8377382

SCHEMBL8377382

CCCC(=O)Oc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NR1H4 Q96RI1 1/20 0.35
NPC1 O15118 3/20 0.35
RAB9A P51151 3/20 0.35
VCAM1 P19320 7/20 0.34
CA2 P00918 2/20 0.33
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TP53 P04637 2/20 0.32
GAA P10253 2/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
GLA P06280 1/20 0.32
KMT2A Q03164 1/20 0.32
BCL9 O00512 1/20 0.31
CTNNB1 P35222 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28646965 0.92 VCAM1 (0.38) NPC1RAB9AVCAM1CA2ALDH1A1
SCHEMBL8377454 0.92 VCAM1 (0.38) NPC1RAB9AVCAM1CA2ALDH1A1
SCHEMBL8376178 0.92 NR1H4 (0.36) NR1H4NPC1RAB9AVCAM1MAPT
SCHEMBL29152914 0.89 NPC1 (0.42) NPC1RAB9AVCAM1MAPTKDM4E
SCHEMBL8384145 0.88 GAA (0.38) NR1H4NPC1RAB9AVCAM1MAPT
SCHEMBL22283789 0.84 NR1H4 (0.36) NR1H4NPC1RAB9ACA2MAPT
SCHEMBL21586951 0.82 PDE2A (0.35) NR1H4NPC1RAB9AMAPTALDH1A1
SCHEMBL12199840 0.82 CA1 (0.48) NR1H4NPC1RAB9ACA2MAPT
SCHEMBL29791013 0.80 NPC1 (0.43) NPC1RAB9AVCAM1MAPTKDM4E
SCHEMBL8580605 0.80 NPC1 (0.43) NPC1RAB9AVCAM1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117715879-A Interlayer film for laminated glass and laminated glass 积水化学工业株式会社 2024-03-15 CN disclosed
CN-117677592-A Interlayer film for laminated glass and laminated glass 积水化学工业株式会社 2024-03-08 CN disclosed
CN-117425635-A Resin film, laminated glass and screen 积水化学工业株式会社 2024-01-19 CN disclosed
CN-117425634-A Resin film, laminated glass and screen 积水化学工业株式会社 2024-01-19 CN disclosed
CN-117396448-A Resin film, laminated glass and screen 积水化学工业株式会社 2024-01-12 CN disclosed
CN-113573900-B Thermoplastic film and laminated glass 积水化学工业株式会社 2023-09-15 CN disclosed
CN-113573890-B Thermoplastic film and laminated glass 积水化学工业株式会社 2023-06-06 CN disclosed
CN-113573889-B Thermoplastic film and laminated glass 积水化学工业株式会社 2023-05-26 CN disclosed
CN-116082989-A Interlayer film for laminated glass and laminated glass 积水化学工业株式会社 2023-05-09 CN disclosed
CN-111757860-B Interlayer film for laminated glass and laminated glass 积水化学工业株式会社 2023-02-28 CN disclosed
US-20200391487-A1 LAMINATED GLASS INTERMEDIATE FILM AND LAMINATED GLASS SEKISUI CHEMICAL CO., LTD. (JP) 2020-12-17 US disclosed
CN-111757860-A Interlayer film for laminated glass and laminated glass 积水化学工业株式会社 2020-10-09 CN disclosed
CN-111201457-A Glass structure 积水化学工业株式会社 2020-05-26 CN disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5902516-A STABILIZER FOR THERMOPLASTIC POLYOLEFIN OR ENGINEERING RESINS SUMITOMO CHEMICAL CO., LTD (JP) 1999-05-11 US disclosed
US-5891939-A POLYMER STABILIZERS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-04-06 US disclosed
US-5874494-A DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-23 US disclosed
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed
US-5843339-A Phosphites and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-01 US disclosed
US-5830936-A THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-11-03 US disclosed