SCHEMBL8384145

SCHEMBL8384145

CCCCC(CC)CCCC(=O)Oc1cc(-n2nc3ccc(Cl)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
XBP1 P17861 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALDH1A1 P00352 2/20 0.35
MAPK1 P28482 1/20 0.35
VCAM1 P19320 4/20 0.32
NR1H4 Q96RI1 1/20 0.31
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28646965 0.90 VCAM1 (0.38) ALDH1A1MAPK1VCAM1NPC1HPGD
SCHEMBL8377454 0.90 VCAM1 (0.38) ALDH1A1MAPK1VCAM1NPC1HPGD
SCHEMBL8377382 0.88 NR1H4 (0.35) GAAALDH1A1VCAM1NR1H4KDM4E
SCHEMBL8376178 0.84 NR1H4 (0.36) GAANPSR1L3MBTL1ALDH1A1MAPK1
SCHEMBL76644 0.81 ALDH1A1 (0.43) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL29496845 0.81 ALDH1A1 (0.43) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL19834895 0.81 ALDH1A1 (0.44) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL28876135 0.81 ALDH1A1 (0.43) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL27747901 0.80 ATM (0.49) GAAXBP1ATMNPSR1L3MBTL1
SCHEMBL21586951 0.79 PDE2A (0.35) GAAL3MBTL1ALDH1A1NR1H4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5902516-A STABILIZER FOR THERMOPLASTIC POLYOLEFIN OR ENGINEERING RESINS SUMITOMO CHEMICAL CO., LTD (JP) 1999-05-11 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
US-5874494-A DETERIORATION STABILIZER FOR THERMOPLASTIC RESIN; OXIDATION RESISTANCE, DISCOLORATION INHIBITION, HEAT RESISTANCE, CROSSLINKING INHIBITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-23 US disclosed
US-5847187-A Organic phosphorous compound, a process for producing the same and a use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-08 US disclosed
US-5843339-A Phosphites and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-12-01 US disclosed
US-5830936-A THERMAL STABILIZERS FOR POLYOLEFINS AND ENGINEERING PLASTICS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-11-03 US disclosed