SCHEMBL8378148

SCHEMBL8378148

CCc1ccc(/C=C/c2cnccn2)cc1

nearest known ligand 0.63

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.63
KMT2A Q03164 4/20 0.63
DHFR P00374 1/20 0.43
ALOX5 P09917 1/20 0.42
PTGS1 P23219 1/20 0.42
PTGS2 P35354 1/20 0.42
NPC1 O15118 3/20 0.42
MAPT P10636 3/20 0.41
TUBB1 Q9H4B7 1/20 0.41
MEN1 O00255 2/20 0.40
MAOB P27338 2/20 0.39
ALDH1A1 P00352 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3792835 1.00 RAB9A (0.63) RAB9AKMT2ADHFRALOX5PTGS1
SCHEMBL29240838 0.86 RAB9A (0.81) RAB9AKMT2ANPC1MAPTMEN1
SCHEMBL30990554 0.86 RAB9A (0.81) RAB9AKMT2ANPC1MAPTMEN1
SCHEMBL317844 0.84 MAPT (0.56) RAB9AKMT2ADHFRALOX5PTGS1
SCHEMBL317843 0.84 MAPT (0.56) RAB9AKMT2ADHFRALOX5PTGS1
SCHEMBL1178920 0.81 RAB9A (0.69) RAB9AKMT2ADHFRALOX5PTGS1
SCHEMBL1178923 0.81 RAB9A (0.69) RAB9AKMT2ADHFRALOX5PTGS1
SCHEMBL5651348 0.80 DHFR (0.51) RAB9AKMT2ADHFRALOX5PTGS1
SCHEMBL5651345 0.80 DHFR (0.51) RAB9AKMT2ADHFRALOX5PTGS1
SCHEMBL3469355 0.78 MAPT (0.50) RAB9AKMT2ADHFRALOX5PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5857886-A FORMING TRANSPARENT ELECTRODE, FORMING CARBON FILM, FORMING ORGANIC THIN FILM LAYER, FORMING ELECTRON INJECTION ELECTRODE MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1999-01-12 US disclosed
US-5710484-A Organic thin film electroluminescent device having a carbon layer between the hole injection layer and the organic thin film layer MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1998-01-20 US disclosed