Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.34 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8378417 | 1.00 | HSD17B10 (0.46) | HSD17B10CA1CA2PARP15PARP10 | |
| SCHEMBL10499787 | 0.79 | CA2 (0.55) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL10622883 | 0.78 | MAOB (0.55) | HSD17B10CA1CA2ALDH1A1NOS3 | |
| SCHEMBL786739 | 0.78 | MIF (0.52) | HSD17B10CA1CA2ALDH1A1MAPT | |
| SCHEMBL31054334 | 0.77 | ALDH1A1 (0.53) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL12812881 | 0.77 | MAOA (0.58) | HSD17B10CA1CA2GSK3BMAPT | |
| SCHEMBL11632806 | 0.77 | MAOA (0.53) | CA1CA2GSK3BALDH1A1MAPT | |
| SCHEMBL10499637 | 0.75 | PARP15 (0.42) | CA1CA2PARP15PARP10PARP2 | |
| SCHEMBL8378367 | 0.75 | HSD17B10 (0.50) | HSD17B10MAPTP2RY6 | |
| SCHEMBL10500433 | 0.74 | MAPT (0.49) | HSD17B10CA1CA2PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0664825-B1 | THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | SECR DEFENCE BRIT (GB) | 1999-03-31 | — | — | EP | disclosed |
| US-5578242-A | LIQUID CRYSTALS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF DEFENCE RESEARCH AGENCY (GB) | 1996-11-26 | — | — | US | disclosed |
| EP-0664825-A1 | THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND (GB) | 1995-08-02 | — | — | EP | disclosed |
| WO-1994009085-A1 | THIO-ESTER COMPOUNDS AND MIXTURES AND DEVICES CONTAINING SUCH COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND OF THE DEFENCE RESEARCH AGENCY (GB) | 1994-04-28 | — | — | WO | disclosed |