Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | P4HB | P07237 | 2/20 | 0.50 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603880 | 0.85 | MAPT (0.50) | CA2CA12CA3CA6CA9 | |
| SCHEMBL31054334 | 0.85 | ALDH1A1 (0.53) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL12812881 | 0.85 | MAOA (0.58) | CA2CA1GSK3BMAOAMAOB | |
| SCHEMBL11632806 | 0.84 | MAOA (0.53) | CA2CA1GSK3BMAOAMAOB | |
| SCHEMBL10500433 | 0.79 | MAPT (0.49) | CA2CA1PARP15PARP10PARP2 | |
| SCHEMBL8378417 | 0.79 | HSD17B10 (0.46) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL8378450 | 0.79 | HSD17B10 (0.46) | CA2CA1GSK3BPARP15PARP10 | |
| SCHEMBL5962921 | 0.77 | CA2 (0.70) | CA2CA12CA3CA6CA9 | |
| SCHEMBL10500354 | 0.77 | MAPK1 (0.59) | CA2CA1MAOBMAPTESR1 | |
| SCHEMBL10500136 | 0.77 | CES2 (0.45) | CA2CA12CA3CA6CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4849419-A | 7-oxo-4-thia-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1989-07-18 | — | — | US | disclosed |
| EP-0174561-A1 | 7-Oxo-4-thia-1-azabicyclo[3,2,0]hept-2-ene derivatives | HOECHST UK LIMITED (GB) | 1986-03-19 | — | — | EP | disclosed |