Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.30 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.30 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.30 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.30 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.30 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945843 | 0.73 | MAPT (0.33) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL6491041 | 0.72 | ALDH1A1 (0.38) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL9739643 | 0.68 | MAPT (0.37) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL5538032 | 0.67 | MAPT (0.38) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL7672004 | 0.66 | MAPT (0.38) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL20710 | 0.65 | — | — | |
| SCHEMBL5542218 | 0.65 | MAPT (0.48) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL3363357 | 0.62 | MAPT (0.50) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL8725842 | 0.61 | MAPT (0.47) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL526383 | 0.61 | MAPT (0.58) | MAPTKDM4EALDH1A1POLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929114-A | ADMINISTERING ANTIVIRAL COMPOUND WHICH EXTRUDES ZINC FROM NUCLEOCAPSID PROTEIN OF HUMAN IMMUNODEFICIENCY VIRUS | WARNER-LAMBERT COMPANY (US) | 1999-07-27 | — | — | US | claimed |
| US-5929114-A | ADMINISTERING ANTIVIRAL COMPOUND WHICH EXTRUDES ZINC FROM NUCLEOCAPSID PROTEIN OF HUMAN IMMUNODEFICIENCY VIRUS | WARNER-LAMBERT COMPANY (US) | 1999-07-27 | — | — | US | disclosed |
| US-5734081-A | Arylthio compounds | WARNER-LAMBERT COMPANY (US) | 1998-03-31 | — | — | US | disclosed |