Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PHGDH | O43175 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1799068 | 0.96 | ALDH1A1 (0.64) | ALDH1A1HSD17B10POLBPHGDHHPGD | |
| SCHEMBL11070729 | 0.90 | KMT2A (0.59) | ALDH1A1HSD17B10POLBPHGDHHPGD | |
| SCHEMBL24120195 | 0.87 | HPGD (0.61) | ALDH1A1HSD17B10POLBPHGDHHPGD | |
| SCHEMBL11068661 | 0.86 | ALDH1A1 (0.64) | ALDH1A1HSD17B10POLBPHGDHHPGD | |
| SCHEMBL7824233 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HSD17B10POLBPHGDHHPGD | |
| Ethylene SCHEMBL8381019 | 0.84 | MTHFD2 (0.51) | ALDH1A1HPGDKMT2ACA12CA1 | |
| SCHEMBL10722382 | 0.83 | POLB (0.81) | ALDH1A1HSD17B10POLBPHGDHHPGD | |
| SCHEMBL9585721 | 0.83 | POLB (0.81) | ALDH1A1HSD17B10POLBPHGDHHPGD | |
| Ethylene SCHEMBL8378361 | 0.83 | HPGD (0.66) | ALDH1A1POLBHPGDMGLLKMT2A | |
| Ethylene SCHEMBL8378372 | 0.83 | HSD11B1 (0.55) | ALDH1A1POLBMGLLKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |