Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7434597 | 0.96 | HSD11B1 (0.58) | HSD11B1CA12CA1CA2CA7 | |
| SCHEMBL24120195 | 0.87 | HPGD (0.61) | L3MBTL1POLBMEN1ALDH1A1KMT2A | |
| SCHEMBL25331094 | 0.84 | HSD11B1 (0.57) | HSD11B1CA12CA1CA2CA7 | |
| Ethylene SCHEMBL8381019 | 0.84 | MTHFD2 (0.51) | CA12CA1CA9MEN1ALDH1A1 | |
| SCHEMBL6985975 | 0.83 | CA12 (0.71) | HSD11B1CA12CA1CA2CA7 | |
| SCHEMBL22305103 | 0.83 | CA12 (0.71) | HSD11B1CA12CA1CA2CA7 | |
| Ethylene SCHEMBL8379754 | 0.83 | ALDH1A1 (0.60) | CA12CA1CA2CA7CA9 | |
| Ethylene SCHEMBL8378361 | 0.83 | HPGD (0.66) | HSD11B1CA12CA1CA2CA7 | |
| Ethylene SCHEMBL8380995 | 0.83 | PKM (0.61) | HSD11B1MEN1ALDH1A1KMT2AMGLL | |
| Ethylene SCHEMBL8381008 | 0.83 | SMN1; SMN2 (0.45) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883102-A | Pharmaceutically active compounds | ASTRA PHARMACEUTICALS LIMITED (GB) | 1999-03-16 | — | — | US | disclosed |