SCHEMBL8380375

SCHEMBL8380375

[SiH3][SiH]([SiH3])Cc1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.45
TSHR P16473 4/20 0.41
ALDH1A1 P00352 3/20 0.41
IDO1 P14902 3/20 0.41
LOXL2 Q9Y4K0 2/20 0.41
TP53 P04637 1/20 0.41
TRPA1 O75762 1/20 0.41
MAOB P27338 1/20 0.39
HPGD P15428 1/20 0.39
ALOX15 P16050 1/20 0.39
ALOX12 P18054 1/20 0.39
CASP1 P29466 1/20 0.39
HSD17B10 Q99714 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
CYP2A6 P11509 1/20 0.38
HTR2A P28223 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
THRB P10828 1/20 0.36
EPHX2 P34913 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25364772 0.78 LOXL2 (0.43) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL3482200 0.78 TSHR (0.43) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL29875499 0.78 TP53 (0.43) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL8381385 0.76 CALM1 (0.39) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL41196 0.75 CALM1 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
Hydrochloric Acid SCHEMBL29160220 0.73 CALM1 (0.47) CALM1TSHRALDH1A1IDO1LOXL2
Fluoride SCHEMBL27669418 0.73 CALM1 (0.47) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL9422248 0.73 CALM1 (0.47) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL10318631 0.72 LTA4H (0.39) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL8383813 0.72 ALDH1A1 (0.48) CALM1TSHRALDH1A1IDO1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0630933-B1 A method of producing a semiconducting material NIPPON OIL CO LTD (JP) 1999-04-14 EP disclosed
US-5700400-A Method for producing a semiconducting material NIPPON OIL CO., LTD. (JP) 1997-12-23 US disclosed
EP-0551771-B1 Process for producing polysilanes NIPPON OIL CO LTD (JP) 1997-07-30 EP disclosed
US-5620531-A Photovoltaic element NIPPON OIL CO., LTD. (JP) 1997-04-15 US disclosed
EP-0717451-A2 Photovoltaic element NIPPON OIL CO., LTD. (JP) 1996-06-19 EP disclosed
EP-0630933-A2 A method of producing a semiconducting material NIPPON OIL CO. LTD. (JP) 1994-12-28 EP disclosed
US-5304622-A Process for producing polysilanes NIPPON OIL COMPANY, LTD. (JP) 1994-04-19 US disclosed
EP-0551771-A2 Process for producing polysilanes NIPPON OIL CO. LTD. (JP) 1993-07-21 EP disclosed