Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.36 |
| ▸ | CMA1 | P23946 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377427 | 0.75 | NAMPT (0.41) | OPRM1OPRL1 | |
| SCHEMBL6474586 | 0.74 | OPRM1 (0.46) | GRM5OPRM1OPRL1 | |
| SCHEMBL3559706 | 0.74 | NSD2 (0.58) | CTSGCMA1NSD2 | |
| SCHEMBL8379317 | 0.72 | CASP3 (0.38) | OPRM1OPRL1NSD2 | |
| SCHEMBL8377372 | 0.70 | CASP3 (0.37) | OPRM1OPRL1NSD2 | |
| SCHEMBL7394220 | 0.70 | KDM4E (0.41) | — | |
| SCHEMBL7395289 | 0.70 | KDM4E (0.39) | — | |
| SCHEMBL6740517 | 0.70 | POLB (0.46) | OPRM1OPRL1CTSGCMA1 | |
| SCHEMBL7392675 | 0.68 | GRM5 (0.40) | GRM5 | |
| SCHEMBL3541145 | 0.67 | HNF4A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5863947-A | Phenylglycine derivatives useful for treating disorders of the central nervous system | ELI LILLY AND COMPANY LIMITED (GB) | 1999-01-26 | — | — | US | disclosed |