SCHEMBL8380667

SCHEMBL8380667

CC(C)c1cccc(C(C)C)c1OC(=O)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.51
KMT2A Q03164 1/20 0.51
TSHR P16473 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2503264 0.91 TSHR (0.48) LMNAKMT2ATSHR
SCHEMBL2481012 0.90 KMT2A (0.53) LMNAKMT2A
SCHEMBL9959047 0.83 KMT2A (0.43) LMNAKMT2ATSHR
SCHEMBL28017361 0.83 MAPT (0.45) LMNAKMT2ATSHR
SCHEMBL2481453 0.82 SLC6A3 (0.49) LMNAKMT2A
SCHEMBL4333091 0.81 ALDH1A1 (0.45) LMNA
SCHEMBL2504098 0.81 LMNA (0.42) LMNAKMT2ATSHR
SCHEMBL2481455 0.81 PDCD1 (0.43) LMNAKMT2ATSHR
SCHEMBL17069171 0.81 ALDH1A1 (0.56) LMNAKMT2ATSHR
SCHEMBL4023092 0.81 SCN5A (0.49)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0783473-B1 PROCESS FOR THE PURIFICATION OF 2,6-DIISOPROPYLPHENOL ZAMBON SPA (IT) 1999-03-24 EP disclosed
EP-0783473-A1 PROCESS FOR THE PURIFICATION OF 2,6-DIISOPROPYLPHENOL ZAMBON GROUP S.p.A. (IT) 1997-07-16 EP disclosed
US-5589598-A Process of purification of 2,6-diisopropylphenol ZAMBON GROUP S.P.A. (IT) 1996-12-31 US disclosed
WO-1996010004-A1 PROCESS FOR THE PURIFICATION OF 2,6-DIISOPROPYLPHENOL ZAMBON GROUP S.P.A. (IT) 1996-04-04 WO disclosed