Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 11/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 10/20 | 0.39 |
| ▸ | TLR4 | O00206 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437397 | 0.87 | TLR4 (0.34) | FPR2PROKR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9620254 | 0.87 | CCR5 (0.37) | SLC6A3SLC6A2SLC6A4TLR4CRHR1 | |
| SCHEMBL8433543 | 0.85 | MAPK1 (0.34) | SLC6A3SLC6A2SLC6A4TLR4 | |
| SCHEMBL8433409 | 0.85 | SLC6A3 (0.35) | SLC6A3TLR4 | |
| SCHEMBL7913831 | 0.85 | GAA (0.36) | TLR4 | |
| SCHEMBL8437731 | 0.84 | MAOB (0.38) | SLC6A3SLC6A2SLC6A4TLR4 | |
| SCHEMBL9751893 | 0.84 | CYP2C9 (0.49) | TLR4 | |
| SCHEMBL8370943 | 0.83 | PDE2A (0.37) | — | |
| SCHEMBL8435370 | 0.82 | SLC6A2 (0.34) | SLC6A3SLC6A2SLC6A4TLR4 | |
| SCHEMBL9349806 | 0.82 | SLC6A2 (0.34) | SLC6A3SLC6A2SLC6A4TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958290-A | ELECTROOPTICAL APPARATUS WITH DIELECTRIC LIQUID CRYSTALS FOR RADIATION TRANSPARENT MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-09-28 | — | — | US | disclosed |