Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.32 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9620254 | 0.88 | CCR5 (0.37) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8433543 | 0.87 | MAPK1 (0.34) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8380860 | 0.87 | FPR2 (0.41) | TLR4FPR2PROKR1SLC6A2SLC6A3 | |
| SCHEMBL8433409 | 0.87 | SLC6A3 (0.35) | TLR4SLC6A3 | |
| SCHEMBL7913831 | 0.86 | GAA (0.36) | TLR4CYP2C9ALDH1A1HRH3 | |
| SCHEMBL8437731 | 0.85 | MAOB (0.38) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL9751893 | 0.85 | CYP2C9 (0.49) | TLR4CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL8370943 | 0.84 | PDE2A (0.37) | CYP2C9 | |
| SCHEMBL8372785 | 0.83 | HRH3 (0.34) | HRH3 | |
| SCHEMBL8857679 | 0.83 | CCR5 (0.39) | CYP2C9ALDH1A1LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5876626-A | HIGH SPEED SWITCHING | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0394417-B1 | SUPERTWIST LIQUID CRYSTAL DISPLAY | MERCK PATENT GMBH (DE) | 1994-10-26 | — | — | EP | disclosed |
| EP-0394417-A1 | SUPERTWIST LIQUID CRYSTAL DISPLAY. | MERCK PATENT GMBH (DE) | 1990-10-31 | — | — | EP | disclosed |