Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 6/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227942 | 0.93 | PDE2A (0.38) | PDE2ARPS6KB1OPRM1OPRK1OPRL1 | |
| SCHEMBL8433409 | 0.86 | SLC6A3 (0.35) | — | |
| SCHEMBL9620254 | 0.84 | CCR5 (0.37) | CYP2C9 | |
| SCHEMBL8437397 | 0.84 | TLR4 (0.34) | CYP2C9 | |
| SCHEMBL8433543 | 0.83 | MAPK1 (0.34) | CYP2C9TSHR | |
| SCHEMBL8380860 | 0.83 | FPR2 (0.41) | — | |
| SCHEMBL9646657 | 0.83 | PDE2A (0.41) | PDE2AOPRM1TSHR | |
| SCHEMBL7913831 | 0.82 | GAA (0.36) | OPRM1OPRK1OPRL1CYP2C9TACR1 | |
| SCHEMBL8437731 | 0.82 | MAOB (0.38) | CYP2C9 | |
| SCHEMBL9751893 | 0.82 | CYP2C9 (0.49) | CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0494368-B1 | Supertwist liquid crystal display | MERCK PATENT GMBH (DE) | 1999-01-20 | — | — | EP | disclosed |
| EP-0494368-A2 | Supertwist liquid crystal display | MERCK PATENT GmbH (DE) | 1992-07-15 | — | — | EP | disclosed |