SCHEMBL838092

SCHEMBL838092

C=C(C)C(=O)OCCOC(=O)c1ccc(N(CC(=O)O)CC(=O)O)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.45
POLB P06746 1/20 0.45
APEX1 P27695 1/20 0.45
HTT P42858 1/20 0.45
THRB P10828 1/20 0.40
HPGD P15428 2/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.39
LMNA P02545 2/20 0.39
RECQL P46063 1/20 0.38
TSHR P16473 5/20 0.38
ESR1 P03372 3/20 0.38
CHRM1 P11229 1/20 0.38
SLC6A2 P23975 1/20 0.38
KDR P35968 1/20 0.38
PHLPP2 Q6ZVD8 1/20 0.38
ESR2 Q92731 1/20 0.38
MAPK1 P28482 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4071508 0.96 THRB (0.43) TDP1POLBAPEX1HTTTHRB
SCHEMBL12394953 0.96 THRB (0.43) TDP1POLBAPEX1HTTTHRB
SCHEMBL12394954 0.96 THRB (0.43) TDP1POLBAPEX1HTTTHRB
SCHEMBL1696749 0.84 TDP1 (0.54) TDP1POLBAPEX1HTTTHRB
SCHEMBL44949 0.83 ALDH1A1 (0.52) TDP1POLBAPEX1HTTTHRB
SCHEMBL13681073 0.81 TDP1 (0.42) TDP1POLBAPEX1HTTTHRB
SCHEMBL1152389 0.81 TDP1 (0.64) TDP1POLBAPEX1HTTTHRB
SCHEMBL12699507 0.81 POLB (0.39) TDP1POLBAPEX1HTTTHRB
SCHEMBL12981489 0.80 TDP1 (0.36) TDP1POLBAPEX1HTTTHRB
SCHEMBL18708839 0.80 TSHR (0.44) TDP1POLBAPEX1HTTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9032876-B2 Lithographic printing plate precursor, lithographic printing plate platemaking method, and polymerizable monomer FUJIFILM CORPORATION (JP) 2015-05-19 US disclosed
US-8426102-B2 Lithographic printing plate precursor and plate making method FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
US-8399172-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2013-03-19 US disclosed
US-8309294-B2 2012-11-13 US disclosed
US-8304171-B2 Plate making method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-11-06 US disclosed
US-8257913-B2 Processing method of lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2012-09-04 US disclosed
US-8221957-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8187791-B2 Lithographic printing plate precursor and plate making method thereof FUJIFILM CORPORATION (JP) 2012-05-29 US disclosed
US-8142978-B2 Planographic printing plate precursor and printing method using the same FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-8142983-B2 Lithographic printing plate precursor and method of lithographic printing FUJIFILM CORPORATION (JP) 2012-03-27 US disclosed
US-20070231745-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070214987-A1 Lithographic printing plate precursor FUJIFILM CORPORATION 2007-09-20 US disclosed
US-20070207411-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-09-06 US disclosed
US-20070202443-A1 Method for processing lithographic printing plate precursor, plate inspection method, image quality control method and dyeing aqueous solution used therein FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070184387-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-08-09 US disclosed
US-20070134587-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2007-06-14 US disclosed
US-20070128550-A1 Method for preparation of lithographic printing plate and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-06-07 US disclosed
US-20070072119-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070056457-A1 Lithographic printing plate precursor, lithographic printing method, and novel cyanine dye FUJI PHOTO FILM CO., LTD. 2007-03-15 US disclosed
US-20070042293-A1 Including an aromatic diphosphonium compound along with an addition polymerization promoter, unsaturated compound, protective layeron an sluminium support; laser recording having excellent ink receptibility during printing and printing durability; strength; on-press development; image strength FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed