SCHEMBL44949

SCHEMBL44949

C=C(C)C(=O)OCCOC(=O)c1ccc(N(C)C)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.52
MAPT P10636 6/20 0.52
HPGD P15428 4/20 0.52
NPC1 O15118 4/20 0.51
KDM4E B2RXH2 4/20 0.51
RAB9A P51151 4/20 0.51
HSD17B10 Q99714 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
GAA P10253 2/20 0.51
TSHR P16473 2/20 0.51
MAPK1 P28482 2/20 0.51
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TDP1 Q9NUW8 2/20 0.46
POLB P06746 1/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
PHLPP2 Q6ZVD8 1/20 0.44
THRB P10828 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1696749 0.89 TDP1 (0.54) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL278599 0.87 PHLPP2 (0.48) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL1506126 0.87 ALDH1A1 (0.65) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL16351937 0.84 TDP1 (0.50) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL16351931 0.84 TDP1 (0.50) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL5299649 0.83 ALDH1A1 (0.54) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL7698399 0.83 THRB (0.45) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL5579297 0.83 ALDH1A1 (0.51) ALDH1A1MAPTHPGDNPC1KDM4E
SCHEMBL838092 0.83 TDP1 (0.45) ALDH1A1MAPTHPGDNPC1RAB9A
SCHEMBL24199832 0.83 TDP1 (0.49) ALDH1A1MAPTHPGDNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552300-A Method for realizing anti-caking of acrylic resin powder by chemical doping method 博立尔化工(扬州)有限公司 2025-03-04 CN claimed
US-5717217-A Method for determining thickness, degree of cure and other properties of a polymeric coating SPECTRA GROUP LIMITED, INC. (US) 1998-02-10 US claimed
EP-0509516-B1 Dental restoration composition SANKIN IND CO (JP) 1997-03-26 EP claimed
US-5606171-A USING A FLUORESCENT DETECTOR SPECTRA GROUP LIMITED, INC. (US) 1997-02-25 US claimed
WO-1994014410-A1 NEW SUNBLOCKING POLYMERS AND THEIR FORMULATION BIOPHYSICA, INC. (US) 1994-07-07 WO claimed
US-5306338-A Powder of fluoride-releasing glass filler, accelerator to be mixed with liquid of dimethacrylate monomers, water soluble methacryloxyalkyl phosphate, photoinitiator, diluent SANKIN KOGYO K.K. (JP) 1994-04-26 US claimed
WO-1994000096-A1 DENTAL ADHESIVE PRIMER COMPOSITION AND DENTIN CONDITIONING PRIMER COMPOSITION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1994-01-06 WO claimed
EP-0509516-A2 Dental restoration composition SANKIN KOGYO KABUSHIKI KAISHA (JP) 1992-10-21 EP claimed
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP claimed
EP-4736835-A1 DENTAL POLYMERIZABLE COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-05-06 EP disclosed
US-12617887-B2 Resin composition for stereolithography KURARAY NORITAKE DENTAL INC. (JP) 2026-05-05 US disclosed
EP-3862373-B1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTAL INC (JP) 2026-04-22 EP disclosed
EP-4722266-A1 STEREOLITHOGRAPHIC RESIN COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-08 EP disclosed
US-12564543-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2026-03-03 US disclosed
US-4485161-A Electrophotographic elements having barrier layers of crosslinked polymers of aliphatic or aromatic monomers containing α,β-ethylenically unsaturated carbonyl-containing substituents EASTMAN KODAK COMPANY (US) 1984-11-27 US disclosed
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP disclosed
US-4366228-A 3-KETOCOUMARIN DERIVATIVES AS PHOTOSENSITIZERS; ALPHA-PHENYLOXYALKYLENECARBOXYLIC ACIDS AS ACTIVATORS; HIGH SPEED EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4289844-A 3-KETO-COUMARIN DERIVATIVES, HIGH SPEED EASTMAN KODAK COMPANY (US) 1981-09-15 US disclosed
EP-0022188-A2 Co-initiator compositions for photopolymerization containing 3-acyl-substituted coumarins, photopolymerizable composition and photographic element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-01-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564543-B2 Dental composition CAD, ARCN1, MAT1A ALDH1A1 306/4885MAPT 344/4885HPGD 1651/4885
US-12617887-B2 Resin composition for stereolithography MAT2B, MAT1A, ARCN1 ALDH1A1 339/4885MAPT 2407/4885HPGD 1604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.