Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12394954 | 1.00 | THRB (0.43) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL12394953 | 1.00 | THRB (0.43) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL838092 | 0.96 | TDP1 (0.45) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL12394967 | 0.81 | ALDH1A1 (0.49) | THRBTDP1ABCB11CYP3A4ADRA2B | |
| SCHEMBL12394958 | 0.81 | ALDH1A1 (0.49) | THRBTDP1ABCB11CYP3A4ADRA2B | |
| SCHEMBL12394957 | 0.81 | ALDH1A1 (0.49) | THRBTDP1ABCB11CYP3A4ADRA2B | |
| SCHEMBL1696749 | 0.81 | TDP1 (0.54) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL44949 | 0.80 | ALDH1A1 (0.52) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL17034393 | 0.80 | ESR1 (0.57) | THRBTDP1POLBAPEX1HTT | |
| SCHEMBL11977028 | 0.79 | NPC1 (0.39) | TDP1HPGDALDH1A1MAPTCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140224140-A1 | PRINTING METHOD USING LITHOGRAPHIC PRINTING PLATE PRECURSOR OF ON-PRESS DEVELOPMENT TYPE | FUJIFILM COPORATION (JP) | 2014-08-14 | — | — | US | disclosed |
| US-20120227605-A1 | ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE, LITHOGRAPHIC PRINTING PLATE SUPPORT, PRESENSITIZED PLATE, METHOD OF MANUFACTURING ALUMINUM ALLOY PLATE FOR LITHOGRAPHIC PRINTING PLATE AND METHOD OF MANUFACTURING LITHOGRAPHIC PRINTING PLATE SUPPORT | FUJIFILM CORPORATION (JP) | 2012-09-13 | — | — | US | disclosed |
| US-20120103220-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR | SONOKAWA KOJI (JP) | 2012-05-03 | — | — | US | disclosed |
| US-20110168044-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110159437-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-06-30 | — | — | US | disclosed |
| US-20110134411-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR, LITHOGRAPHIC PRINTING METHOD AND PACKAGED BODY OF LITHOGRAPHIC PRINTING PLATE PRECURSORS | MITSUMOTO TOMOYOSHI | 2011-06-09 | — | — | US | disclosed |
| US-7939240-B2 | Lithographic printing plate precursor and method of producing printing plate | FUJIFILM CORPORATION (JP) | 2011-05-10 | — | — | US | disclosed |
| US-20110091814-A1 | PROCESS FOR MAKING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2011-04-21 | — | — | US | disclosed |
| US-20110054212-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS | OOHASHI HIDEKAZU | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110054212-A1 | LITHOGRAPHIC PRINTING PLATE PRECURSOR AND LITHOGRAPHIC PRINTING PROCESS | FLNA, PFN1, FLNB | THRB 3699/4885TDP1 1843/4885POLB 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.