Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 3/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAK1 | Q16611 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644252 | 1.00 | ALDH1A1 (0.53) | ALDH1A1NPSR1LMNAGAAL3MBTL1 | |
| SCHEMBL644486 | 0.89 | ALDH1A1 (0.52) | ALDH1A1NPSR1LMNAGAAL3MBTL1 | |
| SCHEMBL6010342 | 0.87 | MMP1 (0.61) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL8384891 | 0.87 | MMP1 (0.61) | MMP1MMP9MMP13ADAM17MMP2 | |
| SCHEMBL926644 | 0.87 | NPSR1 (0.50) | ALDH1A1NPSR1LMNAGAAL3MBTL1 | |
| SCHEMBL927146 | 0.87 | ALDH1A1 (0.50) | ALDH1A1NPSR1LMNAL3MBTL1MCL1 | |
| SCHEMBL28751377 | 0.87 | LMNA (0.52) | ALDH1A1NPSR1LMNAL3MBTL1MCL1 | |
| SCHEMBL18041161 | 0.86 | LMNA (0.67) | ALDH1A1NPSR1LMNAL3MBTL1MAPT | |
| SCHEMBL5569768 | 0.86 | LMNA (0.67) | ALDH1A1NPSR1LMNAL3MBTL1MAPT | |
| SCHEMBL15280427 | 0.86 | LMNA (0.67) | ALDH1A1NPSR1LMNAL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866587-A | HYDROXAMIDE DERIVATIVES OF FUSED PIPERIDINE DERIVATIVES | ADIR ET COMPAGNIE (FR) | 1999-02-02 | — | — | US | disclosed |