SCHEMBL8385271

SCHEMBL8385271

C=Cc1ccccc1COC(=O)c1ccc(O)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.55
KMT2A Q03164 3/20 0.51
MEN1 O00255 1/20 0.51
ESR1 P03372 4/20 0.48
ESR2 Q92731 2/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA7 P43166 1/20 0.47
CA9 Q16790 1/20 0.47
CA14 Q9ULX7 1/20 0.47
PPARG P37231 1/20 0.47
TSHR P16473 3/20 0.45
SLC6A2 P23975 2/20 0.45
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 1/20 0.45
CHRM1 P11229 1/20 0.45
KDR P35968 1/20 0.45
CYBB P04839 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5143591 0.91 PPARG (0.56) LMNAKMT2APPARGTSHRSLC6A2
SCHEMBL10943977 0.87 CA12 (0.46) LMNAKMT2ACA12CA1CA2
SCHEMBL10719292 0.84 TYR (0.55) CYBB
SCHEMBL4070163 0.84 LMNA (0.70) LMNAKMT2AMEN1ESR1ESR2
SCHEMBL22619968 0.82 PPARG (0.42) LMNAKMT2AESR1ESR2PPARG
SCHEMBL1131577 0.81 TDP1 (0.56) LMNAKMT2ATSHRTDP1ALDH1A1
SCHEMBL8707996 0.80 SERPINE1 (0.55) CA12CA1CA2CA7CA9
Hydroquinone SCHEMBL4865328 0.79 ALDH1A1 (0.38) LMNAKMT2AMEN1ESR1ESR2
SCHEMBL2029842 0.78 THRB (0.46) LMNAPPARGTSHRALDH1A1MAPK1
SCHEMBL61037 0.78 ALDH1A1 (0.50) LMNAKMT2AALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6001932-A ACRYLIC ESTER COPOLYMER WITH VINYL ETHER, VINYL ESTER COPOLYMERS FOR RUBBER BLENDS NIPPON MEKTRON, LIMITED (JP) 1999-12-14 US disclosed
EP-0761702-B1 Novel acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON KK (JP) 1999-10-27 EP disclosed
EP-0755952-B1 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON KK (JP) 1999-10-20 EP disclosed
US-5959037-A IMPROVED COLD RESISTANCE AND AN INTERMEDIATE HEAT RESISTANCE BETWEEN THE HEAT RESISTANCE OF ACRYLIC COPOLYMER ELASTOMER AND THAT OF FLUORINE-CONTAINING ELASTOMER WHEN BLENDED WITH THE FLUORINE-CONTAINING ELASTOMER NIPPON MEKTRON, LIMITED (JP) 1999-09-28 US disclosed
EP-0765890-B1 Process for producing rubber compound NIPPON MEKTRON KK (JP) 1999-07-21 EP disclosed
US-5859144-A PREPARING AQUEOUS EMULSION OF FLUORINE-CONTAINING ELASTOMER BY EMULSION POLYMERIZATION USING FLUORINE-CONTAINING SURFACTANT, ADDING ACRYLIC MONOMER, REACTING BY RADICAL POLYMERIZATION NIPPON MEKTRON, LIMITED (JP) 1999-01-12 US disclosed
US-5744562-A GOOD HEAT RESISTANCE AND AMINE RESISTANCE WITH FLUORINE-CONTAINING ELASTOMER NIPPON MEKTRON, LIMITED (JP) 1998-04-28 US disclosed
EP-0765890-A2 Process for producing rubber compound NIPPON MEKTRON, LTD. (JP) 1997-04-02 EP disclosed
EP-0761702-A2 Novel acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON, LTD. (JP) 1997-03-12 EP disclosed
EP-0755952-A2 Acrylic copolymer elastomer, its blend rubber and blend rubber composition NIPPON MEKTRON, LTD. (JP) 1997-01-29 EP disclosed
US-4493884-A O-NAPHTHOQUINONEDIAZIDE AND AROMATIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 1985-01-15 US disclosed