Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRM | P19623 | 4/20 | 0.62 |
| ▸ | SMS | P52788 | 2/20 | 0.62 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.56 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.56 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.56 |
| ▸ | NNMT | P40261 | 1/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.54 |
| ▸ | DPP4 | P27487 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.54 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.54 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.54 |
| ▸ | GAPDH | P04406 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | STAT6 | P42226 | 1/20 | 0.54 |
| ▸ | PI4KA | P42356 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4071842 | 0.89 | SRM (0.59) | SRMSMSNNMTADORA1SMN1; SMN2 | |
| SCHEMBL5418087 | 0.87 | SRM (0.57) | SRMSMSNNMTADORA1SMN1; SMN2 | |
| SCHEMBL6826790 | 0.87 | SRM (0.59) | SRMSMSDOT1LPRMT7DNMT3B | |
| SCHEMBL230821 | 0.80 | EHMT1 (0.63) | ADORA1SMN1; SMN2EHMT1 | |
| SCHEMBL4333891 | 0.79 | EHMT1 (0.59) | EHMT1 | |
| SCHEMBL397800 | 0.79 | AHCY (0.68) | DOT1LADORA3ADORA2ADPP4MEN1 | |
| SCHEMBL31680251 | 0.79 | AHCY (0.68) | DOT1LADORA3ADORA2ADPP4MEN1 | |
| SCHEMBL30211841 | 0.79 | P2RY2 (0.59) | ADORA1SMN1; SMN2EHMT1 | |
| SCHEMBL29126399 | 0.79 | P2RY2 (0.59) | ADORA1SMN1; SMN2EHMT1 | |
| SCHEMBL23982410 | 0.78 | ADORA3 (0.67) | DOT1LADORA3ADORA2ADPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5928862-A | CONTACTING SAMPLE WITH LABELED POLYNUCLEOTIDE PROBES CAPABLE OF TWO POSTIONS, EITHER BOUND TO EACH OTHER WHERE LABELS CAN INTERACT OR ONE BOUND TO TARGET IN SAMPLE; MONITORING FOR SIGNAL INDICATIVE OF PRESENCE OF TARGET | AMOCO CORPORATION (US) | 1999-07-27 | — | — | US | disclosed |
| EP-0232967-B1 | COMPETITIVE HOMOGENEOUS ASSAY | AMOCO CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| EP-0232967-A2 | Competitive homogeneous Assay | AMOCO CORPORATION (US) | 1987-08-19 | — | — | EP | disclosed |