Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRM | P19623 | 4/20 | 0.59 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.57 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.57 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.57 |
| ▸ | PRMT7 | Q9NVM4 | 1/20 | 0.57 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.57 |
| ▸ | SMS | P52788 | 1/20 | 0.56 |
| ▸ | AHCY | P23526 | 3/20 | 0.56 |
| ▸ | DPP4 | P27487 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.55 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.55 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.55 |
| ▸ | GAPDH | P04406 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | STAT6 | P42226 | 1/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385440 | 0.87 | SRM (0.62) | SRMADORA3ADORA2ADOT1LPRMT7 | |
| SCHEMBL4071842 | 0.84 | SRM (0.59) | SRMSMSADORA1SMN1; SMN2 | |
| SCHEMBL5418087 | 0.83 | SRM (0.57) | SRMSMSADORA1SMN1; SMN2 | |
| SCHEMBL226039 | 0.82 | AHCY (0.63) | ADORA3ADORA2ADOT1LAHCYDPP4 | |
| SCHEMBL15643454 | 0.81 | PRMT5 (0.63) | ADORA3ADORA2ADOT1LAHCYDPP4 | |
| SCHEMBL30211841 | 0.81 | P2RY2 (0.59) | AHCYADORA1SMN1; SMN2EHMT1 | |
| SCHEMBL29126399 | 0.81 | P2RY2 (0.59) | AHCYADORA1SMN1; SMN2EHMT1 | |
| SCHEMBL26692891 | 0.81 | ADORA3 (0.59) | SRMADORA3ADORA2ADOT1LPRMT7 | |
| SCHEMBL26692897 | 0.81 | ADORA3 (0.59) | SRMADORA3ADORA2ADOT1LPRMT7 | |
| SCHEMBL230821 | 0.81 | EHMT1 (0.63) | AHCYADORA1SMN1; SMN2EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6740644-B2 | ADENOSINE DERIVATIVES, AGONISTS AT THE ADENOSINE A1 RECEPTOR | SMITHKLINE BEECHAM CORPORATION | 2004-05-25 | — | — | US | claimed |