Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8384276 | 0.91 | CYP2C19 (0.42) | CYP2C19KDM4EHPGDNPSR1GAA | |
| SCHEMBL8385330 | 0.84 | NAMPT (0.40) | CYP2C19KDM4EHPGDNAMPTABL1 | |
| SCHEMBL8385320 | 0.80 | TGM2 (0.45) | KDM4EGAANAMPTMEN1KMT2A | |
| SCHEMBL8380856 | 0.77 | KMT2A (0.36) | CYP2C19GAAALDH1A1MEN1KMT2A | |
| SCHEMBL8385474 | 0.75 | ITGB3 (0.45) | CYP2C19KDM4EHPGDNPSR1GAA | |
| SCHEMBL8385342 | 0.69 | ITGB3 (0.58) | CYP2C19KDM4EHPGDNAMPTMEN1 | |
| SCHEMBL8384282 | 0.69 | PLA2G2A (0.36) | GAAALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8385553 | 0.68 | MAPT (0.48) | NAMPTEPHX2ALDH1A1MEN1KMT2A | |
| SCHEMBL13017212 | 0.68 | TDP1 (0.44) | ALDH1A1MEN1KMT2AMAPTPOLB | |
| SCHEMBL8386317 | 0.68 | EPHX2 (0.41) | CYP2C19KDM4EHPGDNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908843-A | Piperazine compounds as fibrinogen inhibitors | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1999-06-01 | — | — | US | disclosed |