Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BAX | Q07812 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8682830 | 0.79 | — | — | |
| SCHEMBL3487763 | 0.71 | L3MBTL1 (0.43) | TSHRMAOAMAPTCYP1A2MAPK1 | |
| SCHEMBL17414785 | 0.69 | LTA4H (0.42) | LTA4HTSHRCA4NR1H2BAX | |
| SCHEMBL6161720 | 0.68 | LTA4H (0.41) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL18976617 | 0.68 | LTA4H (0.41) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL11481331 | 0.66 | LTA4H (0.86) | LTA4HTSHRCA4NR1H2BAX | |
| Diphenylether SCHEMBL2461810 | 0.65 | LTA4H (1.00) | LTA4HTSHRCA4NR1H2BAX | |
| Diphenylether SCHEMBL12286 | 0.65 | LTA4H (1.00) | LTA4HTSHRCA4NR1H2BAX | |
| Diphenylether SCHEMBL9061108 | 0.65 | LTA4H (1.00) | LTA4HTSHRCA4NR1H2BAX | |
| Diphenylether SCHEMBL4950525 | 0.65 | LTA4H (1.00) | LTA4HTSHRCA4NR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407100-B1 | HORTICULTURE, AGRICULTURE, WOOD PRESERVATION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-06-18 | — | — | US | claimed |
| CN-116063309-B | Synthesis method of ibrutinib | 北京京卫燕康药物研究所有限公司 | 2023-06-13 | — | — | CN | disclosed |
| CN-116063309-A | Synthesis method of ibrutinib | 北京京卫燕康药物研究所有限公司 | 2023-05-05 | — | — | CN | disclosed |
| US-8143052-B2 | Process for preparing optically active (S or R)-α amino acid and (R or S)-α amino acid ester in one phase organic reaction medium | UBE INDUSTRIES, LTD. (JP) | 2012-03-27 | — | — | US | disclosed |
| US-7915019-B2 | Processes for preparing optically active (S or R)-β-amino acid and optically active (R or S)-β-amino acid ester, and β-amino acid 2-alkoxyethyl ester and optically active (S or R)-β amino acid 2-alkoxyethyl ester | UBE INDUSTRIES, LTD. (JP) | 2011-03-29 | — | — | US | disclosed |
| EP-1840218-B1 | Process for production of optically active (S)- or (R)-beta-amino acids and optically active (R)- or (S)-beta -amino acid esters, and optically active (S)- or (R)-2-alkoxyethyl esters of beta-amino acids. | UBE INDUSTRIES (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-20090117626-A1 | Process for preparing carboxylic acid using surfactant-modified enzyme | UBE INDUSTRIES, LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| US-20090042260-A1 | PROCESS FOR PREPARING OPTICALLY ACTIVE (S OR R)-ALPHA-AMINO ACID AND OPTICALLY ACTIVE (R OR S)-ALPHA-AMINO ACID ESTER | UBE INDUSTRIES, LTD. (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-1942193-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S OR R)-a-AMINO ACID OR OPTICALLY ACTIVE (S OR R)-a -AMINO ACID ESTER | Ube Industries, Ltd. (JP) | 2008-07-09 | — | — | EP | disclosed |
| US-20080038785-A1 | Processes For Preparing Optically Active (S Or R-)-Beta-Amino Acid And Optically Active (R Or S)-Beta-Amino Acid Ester, And Beta-Amino Acid 2-Alkoxyethyl Ester And Optically Active (S Or R)-Beta Amino Acid 2-Alkoxyethyl Ester | UBE INDUSTRIES, LTD. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1887086-A1 | PROCESS FOR PRODUCTION OF CARBOXYLIC ACID USING SURFACTANT-MODIFYING ENZYME | Ube Industries, Ltd. (JP) | 2008-02-13 | — | — | EP | disclosed |
| EP-1840218-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE (S)- OR (R)- BETA-AMINO ACIDS AND OPTICALLY ACTIVE (R)- OR (S)-BETA -AMINO ACID ESTERS, 2-ALKOXYETHYL ESTERS OF -AMINO ACIDS, AND OPTICALLY ACITVE (S)- OR (R)-2-ALKOXYETHYL ESTERS OF -AMINO ACIDS | Ube Industries, Ltd. (JP) | 2007-10-03 | — | — | EP | disclosed |
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | UBE INDUSTRIES, LTD. (JP) | 2006-08-10 | — | — | US | disclosed |
| EP-1621529-A1 | 3-AMINO-3-ARYLPROPIONIC ACID n-ALKYL ESTERS, PROCESS FOR PRODUCTION THEREOF, AND PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE 3-AMINO-3-ARYLPROPIONIC ACIDS AND ESTERS OF THE ANTIPODES THERETO | Ube Industries, Ltd. (JP) | 2006-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060178433-A1 | 3-Amino-3-arylpropionic acid n-alkyl esters, process for production thereof, and process for production of optically active 3-amino-3-arylpropionic acids and esters of the antipodes thereto | ALAD, ARSA, ALDH7A1 | LTA4H 1329/4885TSHR 800/4885CA4 1900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.