Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492137 | 0.82 | CES2 (0.44) | ALOX15LMNACA12CA1CA2 | |
| SCHEMBL8387170 | 0.79 | LMNA (0.51) | ALOX15LMNAALDH1A1MYC | |
| SCHEMBL977553 | 0.77 | ALOX15 (0.40) | ALOX15LMNAHSD17B10ALDH1A1KDM4E | |
| SCHEMBL8492263 | 0.77 | HSD17B10 (0.46) | ALOX15LMNAHSD17B10ALDH1A1ERN1 | |
| SCHEMBL8388409 | 0.77 | ALOX15 (0.37) | ALOX15LMNACA12CA1CA2 | |
| SCHEMBL3540940 | 0.75 | CYP1A2 (0.44) | ALOX15CA12CA1CA2CA7 | |
| SCHEMBL26124969 | 0.75 | ALOX15 (0.53) | ALOX15LMNACA12CA1CA2 | |
| SCHEMBL30172016 | 0.74 | CYP1A2 (0.39) | CYP1A2LCKFYNKDM4EASPH | |
| SCHEMBL1511662 | 0.74 | CYP1A2 (0.39) | CYP1A2LCKFYNKDM4EASPH | |
| SCHEMBL8505793 | 0.73 | LMNA (0.40) | ALOX15LMNACA1CA2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856274-A | 4-benzoyl isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0682659-B1 | 4-Benzoyl isoxazole derivatives, their preparation and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-16 | — | — | EP | disclosed |