Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.57 |
| ▸ | CARM1 | Q86X55 | 6/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | PRMT1 | Q99873 | 5/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD5 | P21918 | 1/20 | 0.48 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3894485 | 0.84 | HTR7 (0.59) | SLC6A2SLC6A4SLC6A3CARM1PRMT1 | |
| SCHEMBL8387614 | 0.83 | CARM1 (0.58) | SLC6A2SLC6A4SLC6A3CARM1PRMT1 | |
| SCHEMBL8391031 | 0.82 | HTR1D (0.63) | SLC6A2SLC6A4DRD2DRD1DRD4 | |
| SCHEMBL8387692 | 0.82 | CHRM2 (0.52) | SLC6A2SLC6A4SLC6A3CARM1CHRM2 | |
| Hydrochloric Acid SCHEMBL8704830 | 0.81 | HTR1D (0.62) | SLC6A2SLC6A4DRD2DRD1DRD4 | |
| Hydrochloric Acid SCHEMBL8699695 | 0.80 | DRD2 (0.66) | SLC6A2SLC6A4SLC6A3HTR2ADRD2 | |
| SCHEMBL8388817 | 0.78 | CARM1 (0.43) | SLC6A2SLC6A4SLC6A3CARM1HRH3 | |
| SCHEMBL11260050 | 0.78 | TAAR1 (0.62) | HRH3KCNH2DRD2DRD1DRD4 | |
| SCHEMBL30589200 | 0.78 | SLC6A4 (0.63) | SLC6A2SLC6A4SLC6A3HRH3HTR2A | |
| SCHEMBL8680742 | 0.78 | SLC6A4 (0.63) | SLC6A2SLC6A4SLC6A3HRH3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750607-B1 | 2-(AMINOALKOXY)PHENYLALKYLAMINES WITH ANTIINFLAMMATORY ACTIVITY | KNOLL AG (DE) | 1999-05-06 | — | — | EP | claimed |
| US-5736568-A | ANTIALLERGENS; IMMUNOMODULANTS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-04-07 | — | — | US | disclosed |