Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387593 | 0.81 | LMNA (0.49) | ALOX15LMNAMCL1ALDH1A1TSHR | |
| SCHEMBL8391702 | 0.79 | LCK (0.40) | ALOX15LCKFYNHSD17B10MCL1 | |
| SCHEMBL8387249 | 0.77 | ALOX15 (0.39) | ALOX15LMNALCKFYNHSD17B10 | |
| SCHEMBL26124969 | 0.76 | ALOX15 (0.53) | ALOX15LMNAHSD17B10CA12CA9 | |
| SCHEMBL17395308 | 0.76 | GPR35 (0.40) | LMNALCKFYNHSD17B10MCL1 | |
| SCHEMBL17395316 | 0.75 | KDM4E (0.37) | ALOX15LCKFYNHSD17B10CA12 | |
| SCHEMBL8492263 | 0.74 | HSD17B10 (0.46) | ALOX15LMNALCKFYNHSD17B10 | |
| SCHEMBL8492758 | 0.74 | LCK (0.39) | ALOX15LCKFYNHSD17B10MCL1 | |
| SCHEMBL8308572 | 0.73 | MCL1 (0.41) | LCKFYNHSD17B10CA12CA9 | |
| SCHEMBL8388404 | 0.71 | LCK (0.37) | ALOX15LCKFYNHSD17B10CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856274-A | 4-benzoyl isoxazoles and their use as herbicides | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0682659-B1 | 4-Benzoyl isoxazole derivatives, their preparation and their use as herbicides | RHONE POULENC AGRICULTURE (GB) | 1997-04-16 | — | — | EP | disclosed |
| EP-0682659-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES. | RHONE POULENC AGRICULTURE (GB) | 1995-11-22 | — | — | EP | disclosed |
| WO-1994018179-A1 | 4-BENZOYL ISOXAZOLES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE LTD (GB) | 1994-08-18 | — | — | WO | disclosed |