Methacrylic Acid

Methacrylic Acid

SCHEMBL8390983

C=C(C)C(=O)O.C=CC=CC=Cc1ccccc1.C=Cc1ccccc1C=C

nearest known ligand 0.48

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.48
MAOB P27338 4/20 0.41
GLA P06280 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
HDAC3 O15379 2/20 0.41
HDAC4 P56524 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC7 Q8WUI4 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC10 Q969S8 2/20 0.41
HDAC11 Q96DB2 2/20 0.41
HDAC8 Q9BY41 2/20 0.41
HDAC6 Q9UBN7 2/20 0.41
HDAC9 Q9UKV0 2/20 0.41
HDAC5 Q9UQL6 2/20 0.41
PSMD14 O00487 1/20 0.39
AKR1C3 P42330 1/20 0.38
ALDH1A1 P00352 3/20 0.37
LMNA P02545 2/20 0.37
TRPA1 O75762 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL574438 0.92 CYP3A4 (0.50) CYP3A4MAOBGLATDP1HDAC3
Methacrylic Acid SCHEMBL27385454 0.86 GLA (0.50) CYP3A4MAOBGLATDP1HDAC3
Methacrylic Acid SCHEMBL15121420 0.84 MAOB (0.58) CYP3A4MAOBGLATDP1HDAC3
Styrene SCHEMBL28745769 0.82 ALDH1A1 (0.52) CYP3A4GLATDP1AKR1C3ALDH1A1
Methacrylic Acid SCHEMBL3020182 0.82 KDM4E (0.41) GLATDP1AKR1C3ALDH1A1LMNA
SCHEMBL6674900 0.82 MAOB (0.56) CYP3A4MAOBGLATDP1HDAC3
Methacrylic Acid SCHEMBL301490 0.82 KDM4E (0.42) GLATDP1AKR1C3ALDH1A1LMNA
Methacrylic Acid SCHEMBL8110276 0.82 KDM4E (0.42) GLATDP1AKR1C3ALDH1A1LMNA
Itaconate SCHEMBL11140941 0.82 ALOX15 (0.42) CYP3A4MAOBGLATDP1HDAC3
Bicarbonate SCHEMBL17180457 0.81 MAOB (0.58) CYP3A4MAOBGLATDP1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0911692-A2 Photothermographic elements FUJI PHOTO FILM CO., LTD. (JP) 1999-04-28 EP claimed
EP-0911692-A2 Photothermographic elements FUJI PHOTO FILM CO., LTD. (JP) 1999-04-28 EP disclosed