Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TOP2A | P11388 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.34 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341312 | 0.92 | POLB (0.38) | POLBSMN1; SMN2CNR2PKMFAAH | |
| SCHEMBL8334265 | 0.83 | CNR2 (0.35) | POLBSMN1; SMN2CNR2KMT2AMEN1 | |
| SCHEMBL8393920 | 0.81 | POLB (0.36) | POLBSMN1; SMN2CNR2PKMKMT2A | |
| SCHEMBL8865201 | 0.80 | CNR2 (0.37) | POLBSMN1; SMN2CNR2PKMFAAH | |
| SCHEMBL8336152 | 0.80 | CNR2 (0.37) | POLBSMN1; SMN2CNR2PKMFAAH | |
| SCHEMBL8335569 | 0.79 | GAA (0.40) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8341129 | 0.79 | CNR2 (0.35) | SMN1; SMN2CNR2LMNAALDH1A1P2RX7 | |
| SCHEMBL8340166 | 0.77 | GAA (0.39) | SMN1; SMN2KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL8333062 | 0.77 | GAA (0.36) | POLBSMN1; SMN2CNR2PKMKMT2A | |
| SCHEMBL8339480 | 0.77 | IARS1 (0.38) | POLBSMN1; SMN2KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |