Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | TOP2A | P11388 | 2/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341312 | 0.92 | POLB (0.38) | CNR2LMNASMN1; SMN2TOP2AALDH1A1 | |
| SCHEMBL8341129 | 0.87 | CNR2 (0.35) | CNR2LMNASMN1; SMN2ALDH1A1P2RX7 | |
| SCHEMBL8392602 | 0.83 | POLB (0.40) | CNR2LMNASMN1; SMN2TOP2AALDH1A1 | |
| SCHEMBL8335615 | 0.77 | ALDH1A1 (0.35) | LMNASMN1; SMN2ALPLALPIALPG | |
| SCHEMBL8334261 | 0.74 | CNR2 (0.39) | CNR2LMNASMN1; SMN2ALPIMAPT | |
| SCHEMBL8333062 | 0.74 | GAA (0.36) | CNR2SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL8339543 | 0.74 | ALDH1A1 (0.33) | LMNATOP2AALPLALPIALPG | |
| SCHEMBL8864424 | 0.73 | CNR2 (0.35) | CNR2LMNASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8336673 | 0.73 | CNR2 (0.35) | CNR2LMNASMN1; SMN2TOP2AKMT2A | |
| SCHEMBL8339956 | 0.73 | S1PR2 (0.33) | LMNATOP2AALPLALPIALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |