Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | P2RX5 | Q93086 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8864424 | 0.92 | CNR2 (0.35) | CNR2PKMKMT2AGPR55PDE4A | |
| SCHEMBL8865030 | 0.82 | KMT2A (0.32) | CNR2PKMKMT2AGPR55PDE4A | |
| SCHEMBL8864676 | 0.82 | LMNA (0.38) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8392602 | 0.80 | POLB (0.40) | CNR2PKMKMT2AGPR55MEN1 | |
| SCHEMBL8864443 | 0.79 | LMNA (0.36) | KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL8864601 | 0.79 | KMT2A (0.40) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8336152 | 0.79 | CNR2 (0.37) | CNR2PKMKMT2AGPR55MEN1 | |
| SCHEMBL8865085 | 0.79 | P2RX7 (0.31) | LMNAP2RX7 | |
| SCHEMBL8864409 | 0.78 | KMT2A (0.31) | CNR2PKMKMT2AGPR55MEN1 | |
| SCHEMBL8864346 | 0.78 | KMT2A (0.34) | KMT2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5633239-A | CARDIOVASCULAR DISORDERS; HYPOGLYCEMIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-05-27 | — | — | US | disclosed |