Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341312 | 0.88 | POLB (0.38) | CNR2P2RX7LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8334265 | 0.87 | CNR2 (0.35) | CNR2P2RX7LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8339583 | 0.81 | — | — | |
| SCHEMBL8865085 | 0.80 | P2RX7 (0.31) | P2RX7LMNA | |
| SCHEMBL8336013 | 0.80 | P2RX7 (0.31) | P2RX7 | |
| SCHEMBL8341149 | 0.79 | KMT2A (0.34) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8392602 | 0.79 | POLB (0.40) | CNR2P2RX7LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8339670 | 0.77 | MEN1 (0.31) | — | |
| SCHEMBL8339030 | 0.77 | MEN1 (0.32) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8340290 | 0.76 | POLB (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977177-A | Substituted benzenesulfonylureas and-thioureas, processes for their preparation and use of pharmaceutical preparations based on these compounds, and medicaments containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-11-02 | — | — | US | disclosed |
| US-5880155-A | TREATMENT OF CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |